Hippocampal subfield-specific alterations in post-stroke dementia with subcortical lesion.

ABSTRACT: The structural and functional characteristics of hippocampal subfields have been extensively studied in dementia, with findings indicating stronger associations with cognitive performance than those observed in the whole hippocampus (HP). However, the impact of post-stroke dementia (PSD) on the structural and functional connectivity between hippocampal subfields and cortical regions remains unclear. The objective of this study is to examine alterations in the functional and structural connectivity between hippocampal subfields and cortical regions in PSD. We collected resting-state functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) data from 24 PSD patients, 36 post-stroke non-demented (PSND) patients, and 21 normal controls (NC). These data were used to estima

SUBMITTER: Xu G 

PROVIDER: S-EPMC12831668 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature