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ABSTRACT: Objective
Obesity and overweight are associated with significant psychosocial burden. Existing patient-reported outcome (PRO) measures only assess a subset of emotion-related concepts that are relevant to individuals living with these conditions. The Weight and Emotions Scale (WES) was developed to enable robust evaluation of the impact of obesity or overweight and the benefits of treatment on patients' emotional functioning.Methods
The WES was developed based on findings from interviews with participants (N = 40) exiting a Phase 2 trial for retatrutide (NCT04881760), a targeted literature review, and interviews with clinicians specialized in obesity medicine (N = 3). Cognitive interviews were conducted with adults with obesity/overweight and ≥ 1 obesity-relat
SUBMITTER: Kanu C
PROVIDER: S-EPMC12832084 | biostudies-literature | 2026 Feb
REPOSITORIES: biostudies-literature