De-prescribing opioids among Medicaid patients with long-term opioid use.

ABSTRACT:

Background

Guidelines encourage deprescribing opioids for long-term opioid patients, especially those using opioids and benzodiazepines, z-drugs, or muscle relaxants ("other respiratory depressants").

Objective

Were long-term opioid patients who were prescribed other respiratory depressants more likely to have deprescribing opioid trajectories?

Design

Cross-sectional retrospective study using pharmacy and professional claims from 2015 to 2019. Adjusted logistic regression models were stratified on low (<50 morphine milligram equivalents; MME) and high (>50 MME) starting opioid doses. We reported predicted probabilities with 95 % confidence intervals.

Subjects

Nevada and Colorado Medicaid beneficiaries 18-64 years old without cancer diagnoses with long-term (120

SUBMITTER: Friedman SA 

PROVIDER: S-EPMC12832118 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature