Classifying depression using blood biomarkers: A large population study.

ABSTRACT:

Background

Depression is a common mood disorder characterized by persistent low mood or lack of interest in activities. People with other chronic medical conditions such as obesity and diabetes are at greater risk of depression. Diagnosing depression can be a challenge for primary care providers and others who lack specialized training for these disorders and have insufficient time for in-depth clinical evaluation. We aimed to create a more objective low-cost diagnostic tool based on patients' characteristics and blood biomarkers.

Methods

Blood biomarker results were obtained from the National Health and Nutrition Examination Survey (NHANES, 2007-2016). A prediction model utilizing random forest (RF) in NHANES (2007-2014) to identify depression was derived and validated inte

SUBMITTER: Lin Z 

PROVIDER: S-EPMC12832146 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature