New models to predict survival of patients with difficult ventilator-weaning diagnosed with community-acquired pneumonia.

ABSTRACT:

Background

High mortality is common in mechanically ventilated patients with severe community-acquired pneumonia (CAP). This study sought to create prediction models and determine factors for the pneumonia patients under difficult ventilator weaning in a respiratory care center.

Methods

In total, 353 CAP and hospital-acquired pneumonia (HAP) patients admitted to a respiratory care center (RCC) from January 1, 2015 to December 31, 2017 were included in this retrospective cohort study. Mortality and weaning risks factors were collected and analyzed for validating the prediction models. The study focuses primarily on CAP patients, with HAP data used to external validation.

Results

Among 270 CAP patients in model testing and validation, CURB-65 (Confusion, Uremia, Respira

SUBMITTER: Chen S 

PROVIDER: S-EPMC12832357 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature