Remnant cholesterol: an independent, dose-dependent risk factor for hyperuricemia in a normolipidemic chinese population.

ABSTRACT:

Backgroud

The association between remnant cholesterol (RC) and hyperuricemia (HUA) remains unclear in the general population with entirely normal lipid profiles and no prior lipid-lowering therapy. This study aimed to investigate the association between RC and HUA in a normolipidemic Chinese population.

Method

We recruited 2,171 participants aged 30-79 years from Rongchang, Chongqing Municipality, southwest China, as part of the China Multi-Ethnic Cohort Study. Logistic regression, restricted cubic spline (RCS), and mediation analyses were applied to evaluate the association between RC and HUA. Furthermore, subgroup and sensitivity analyses were conducted to assess the consistency of the findings.

Results

A total of 2,171 participants were enrolled, with a mean (SD) a

SUBMITTER: Xiong H 

PROVIDER: S-EPMC12832488 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature