Age-related evaluation of skin barrier parameters in retrievers.

ABSTRACT:

Introduction

A disruption in the skin barrier, which serves as the primary defense against external pathogens, can lead to skin disorders. In humans, various factors influence the skin barrier, including age and anatomical site. Research on the canine skin barrier is limited; this study evaluated its function across age groups and anatomical sites in healthy retrievers.

Methods

Forty-five healthy retrievers were included and divided into three age groups: young (2-3 years, n = 15), middle-aged (4-6 years, n = 15), and old (7-8 years, n = 15). The skin barrier parameters, including pH, transepidermal water loss (TEWL), skin hydration, sebum, and surface temperature, were measured at the ear pinnae, axillae, and inguinal region. Statistical analyses were u

SUBMITTER: Lee EH 

PROVIDER: S-EPMC12832543 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature