Application of propensity score matching in prognostic analysis of portal hypertension in hepatocellular carcinoma patients.

ABSTRACT:

Objective

To investigate the impact of portal hypertension on surgical prognosis after hepatectomy for hepatocellular carcinoma and assess the therapeutic value of concomitant splenic modulation procedures.

Methods

We retrospectively analyzed HCC patients who underwent open hepatectomy with intraoperative portal venous pressure (PVP) measurement at our center between January 2013 and January 2020. Portal hypertension (PHT) was defined as PVP ≥ 25 cm H₂O. Patients were categorized as PHT (n = 88) or non-PHT (n = 642). Propensity score matching (1:1) was performed to balance baseline covariates; matched analyses included 59 pairs. Short-term perioperative outcomes and long-term overall survival (OS) and recurrence-free survival (RFS) were compared between groups. Wi

SUBMITTER: Gao Q 

PROVIDER: S-EPMC12832559 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature