Impact of waiting time for treatment on the progression of superficial esophageal squamous cell carcinoma: a single-center retrospective study.

ABSTRACT:

Background

We aimed to identify an acceptable waiting period between the diagnosis of superficial esophageal squamous cell carcinoma (SESCC) and endoscopic submucosal dissection (ESD).

Methods

This retrospective, single-center study included 423 patients with 514 SESCC lesions. All patients underwent image-enhanced magnifying endoscopy at initial evaluation and on the day of ESD. Following three outcomes were assessed: the diagnostic accuracy of tumor invasion depth on the day of ESD using the Japanese Esophageal Society classification; changes in diagnosis between initial and final evaluations across different waiting intervals; and 5-year survival rates based on intrapapillary capillary loop patterns (B1 vs. B2) and waiting duration.

Results

The diagnostic accuracy

SUBMITTER: Maeda H 

PROVIDER: S-EPMC12832587 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature