A diagnostic scoring system for differentiating between benign and malignant cystic ovarian tumors, utilizing imaging features and biomarkers.

ABSTRACT:

Objective

Our study aims to establish and validate a diagnostic scoring system for distinguishing malignant cystic ovarian tumors (MCOTs) from benign cystic ovarian tumors (BCOTs).

Methods

The study population was sourced from two independent hospitals. The subjects included 159 patients with 196 masses (137 in the training cohort and 59 in the validation cohort) who had undergone MRI or CT examinations with pathologically confirmed BCOT or MCOT. Four clinical characteristics, four biomarkers, and 16 imaging features were collected. Univariate analyses and multivariate logistic regression analyses were conducted to identify independent predictors for differentiating MCOTs from BCOTs. The independent predictors were weighted based on regression coefficients to construct a sco

SUBMITTER: Zheng X 

PROVIDER: S-EPMC12832662 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature