A nomogram for predicting sedation-related adverse events in elderly patients undergoing painless gastrointestinal endoscopy.

ABSTRACT:

Background

Elderly patients undergoing painless gastrointestinal endoscopy are at increased risk for sedation-related adverse events (SRAEs) because of their greater physiological vulnerability and higher likelihood of comorbidities. Risk stratification before endoscopy may improve perioperative safety and individualize sedation and management.

Objective

This study aimed to develop and internally validate a Firth-penalized multivariable logistic regression model and nomogram to predict SRAEs in elderly patients undergoing painless gastrointestinal endoscopy.

Methods

Prospective data from 520 patients at least 60 years old who underwent painless gastrointestinal endoscopy between April 2023 and June 2024 at our medical center were randomly divided into a training set (

SUBMITTER: Xu L 

PROVIDER: S-EPMC12832725 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature