Rewiring the aging brain: exergaming modulates brain complexity in older adults.

ABSTRACT:

Introduction

Age-related changes in brain signal complexity are associated with cognitive decline and reduced neural adaptivity in older adults. Exergaming offers a promising prophylactic intervention combining physical and cognitive training. The aim of the present study was to assess how exergaming alters the temporal trajectory of brain signal complexity at rest and during gameplay in older adults.

Methods

Twenty-eight healthy older adults participated in a 4-week exergaming intervention. Electroencephalography was recorded using 64 electrodes at rest (pre- and post-intervention) and during exergaming (pre-, mid-, and post-intervention). Brain signal complexity was quantified using multiscale entropy across 64 time scales on preprocessed signals.

Results

Post-inter

SUBMITTER: Piskin D 

PROVIDER: S-EPMC12832828 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature