Elevated inflammatory index and future risk of stroke in patients with coronary heart disease: a multicenter prospective cohort study.

ABSTRACT:

Background

Previous studies have consistently shown that patients with coronary heart disease (CHD) face an elevated risk of stroke, with inflammation likely playing a significant contributing role. Building on this evidence, the present study aims to investigate the associations between three emerging inflammatory markers and the risk of stroke in patients with CHD, as well as to identify which marker offers the greatest clinical predictive value.

Methods

This study involved 5,289 patients with CHD from three clinical centers. COX regression analysis was conducted to examine the relationships between three inflammatory markers-systemic inflammatory response index (SIRI), systemic immune-inflammation index (SII), and aggregate index of systemic inflammation (AISI)-and the ri

SUBMITTER: Cheng J 

PROVIDER: S-EPMC12832916 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature