Chemotherapy improves survival for patients with lymph node-negative invasive papillary breast cancer with tumors ≥2 cm: a SEER population-based study.

ABSTRACT:

Background

Invasive papillary breast cancer (IPC) is a rare cancer known to have a better prognosis than other breast cancers. This study aimed to explore whether patients with early-stage IPC can benefit from chemotherapy.

Materials and methods

IPC cases diagnosed between 2003 and 2021 were retrieved from the Surveillance, Epidemiology, and End Results (SEER) database. The Kaplan-Meier method and the Cox proportional hazard model were performed to identify significant prognostic factors. To eliminate selection bias and baseline characteristics, propensity score matching (PSM) was used. The primary endpoints were overall survival (OS) and breast cancer-specific survival (BCSS).

Results

A total of 1892 patients were enrolled, and 273 pairs were screened after PSM. Mult

SUBMITTER: Zheng Y 

PROVIDER: S-EPMC12832947 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature