Role of radiotherapy in the multidisciplinary treatment of lacrimal gland adenoid cystic carcinoma.

ABSTRACT:

Background

The optimal treatment approach for lacrimal gland adenoid cystic carcinoma (LGACC) remains controversial.

Objectives

We aim to demonstrate the value of radiotherapy (RT) in the multidisciplinary treatment of LGACC.

Design

This was a retrospective cohort study.

Methods

This study was conducted on 90 patients with LGACC treated from 2002 to 2023. We compared the overall survival (OS), progression-free survival (PFS), recurrence-free survival (RFS), and distant metastasis-free survival (DMFS) between those treated with surgery alone versus surgery plus postoperative radiotherapy (PORT). In addition, the ipsilateral visual outcome and ocular complications were evaluated.

Results

The addition of radiotherapy significantly improved the 5-year RFS (6

SUBMITTER: Wang L 

PROVIDER: S-EPMC12833162 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature