Ga-68-Edotreotide PET/CT SSTR Total Tumor Volume as a Predictor of Outcome in Patients With Metastatic Gastroenteropancreatic Neuroendocrine Tumors.

ABSTRACT: IntroductionThe somatostatin receptor (SSTR) standardized uptake value (SUVmax_sstr) obtained by [⁶⁸Ga]Ga-edotreotide positron emission tomography-computed tomography ([⁶⁸Ga]Ga-SSTR PET/CT) helps recognize patients with metastatic gastroenteropancreatic neuroendocrine tumors (GEP-NETs) who are at a high risk for adverse outcomes. This observational cohort study was conducted to verify whether the SSTR representative tumor volume (RTV_sstr) can provide incremental prognostic information over conventional PET/CT parameters in patients with metastatic disease.MethodsWe retrospectively evaluated patients (48% female) with metastatic GEP-NETs who underwent [⁶⁸Ga]Ga-SSTR PET/CT between January 2022 and November 2023. The mean SUVmax_sstr</

SUBMITTER: Gallicchio R 

PROVIDER: S-EPMC12833188 | biostudies-literature | 2026 Jan-Dec

REPOSITORIES: biostudies-literature