Sodium channel blockers as add-on treatment for unexplained refractory chronic cough: a case report and review.

ABSTRACT:

Introduction

Chronic cough is a common symptom with multiple causes, predominantly respiratory, gastroesophageal, or neurological. However, in rare cases, a vascular anomaly, such as internal jugular vein ectasia (IJVE), may function as a trigger. We report the case of a patient with paroxysmal chronic cough associated with right internal jugular vein ectasia, which responded favorably to anticonvulsant therapy.

Case report

We present the case of a 62-year-old female patient with pulmonary, cardiovascular, and neurological comorbidities, with a two-year history of daily episodes of severe, non-productive cough, refractory to standard symptomatic treatments. ENT, pulmonary, and gastroenterological evaluations did not identify a specific organic cause. The neurological examina

SUBMITTER: Butnariu I 

PROVIDER: S-EPMC12833317 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature