Association of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and atherogenic index of plasma with obstructive sleep apnea.

ABSTRACT:

Background

Obstructive sleep apnea (OSA) is a prevalent sleep disorder associated with metabolic, cardiovascular disorders. The non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and atherogenic index of plasma (AIP) are thought to be better ways to detect cardiovascular diseases than single lipid parameters. The relationship between NHHR or AIP and OSA remains ambiguous.

Methods

454 consecutive patients with suspected OSA were enrolled between June 2023 and February 2025. The OSA was defined as the occurrence of more than 5 apnea-hypopnea index (AHI) events/h. Spearman's rank correlation analysis among the NHHR, AIP, AHI, and lowest SpO₂. Binary logistic regression analysis was conducted to investigate the association be

SUBMITTER: Li G 

PROVIDER: S-EPMC12833340 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature