Development and validation of a predictive model for left ventricular diastolic improvement following catheter ablation in atrial fibrillation with diastolic dysfunction: a retrospective analysis.

ABSTRACT:

Background

The impact of catheter ablation on left ventricular diastolic function in patients with atrial fibrillation (AF) and left ventricular diastolic dysfunction (LVDD) remains poorly characterised. There are no robust tools available to predict improvement in LVDD post-ablation.

Methods

The retrospective study enrolled 141 patients diagnosed with AF and LVDD undergoing ablation. LVDD improvement was defined as a reduction of at least one grade in LVDD grade (LVDDG) within 12 ± 3 months after ablation. The predictive model was constructed using a logistic regression with 10-fold validation with stratification. The performance of the model was evaluated using ROC analysis (AUC), calibration plots, and decision curve analysis (DCA). An exploratory sensitivity analysis app

SUBMITTER: Cao Y 

PROVIDER: S-EPMC12833358 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature