Non-invasive assessment of liver fibrosis staging in chronic hepatitis B patients: combining two-dimensional shear wave elastography with serum indicators.

ABSTRACT:

Objective

This study aimed to evaluate the diagnostic accuracy of a novel approach that combines noninvasive indicators with two-dimensional shear wave elastography (2D SWE) to assess liver fibrosis stages in patients with chronic hepatitis B (CHB), using the Scheuer score as the reference standard.

Methods and materials

2D SWE and serum indicators are commonly used for the noninvasive assessment of liver fibrosis. A total of 102 patients with CHB underwent 2D SWE measurements and serum tests for liver fibrosis markers. Standardized protocols were followed for all diagnostic procedures to ensure reproducibility and consistency. Binary logistic regression was used to generate a combined predictive probability value. Receiver operating characteristic (ROC) curves were used to

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC12833436 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature