Association of Functional, Academic, Motor, and Cognitive Deficits in Graft Failure in Pediatric Liver Transplantation.

ABSTRACT:

Introduction

Predicting graft failure risk in pediatric liver transplantation (LT) recipients could identify areas for improving management. Persistent cognitive, motor, academic, and functional deficits are common in recipients and their impact on graft survival following LT helps inform risk prediction.

Methods

Using SRTR data 2008-2023, we evaluated the cognitive, motor, academic, and functional deficits of LT recipients at time of transplant to 14 years post-LT. We compared all cause graft failure (ACGF) among patients with versus without pre-LT and 1-year post-LT deficits using Cox regression, adjusting for recipient characteristics. We calculated an individual risk score for ACGF.

Results

In 8062 pediatric LT recipients median age 3 (IQR: 1, 10), 28.0%, 29.5%, 3

SUBMITTER: Donnelly C 

PROVIDER: S-EPMC12833829 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature