Antibacterial and proteomic profiling of Morus alba extract against methicillin-resistant Staphylococcus aureus.

ABSTRACT:

Background

Antimicrobial resistance, particularly from methicillin-resistant Staphylococcus aureus (MRSA), is a growing global health threat. Alternative therapies derived from medicinal plants are gaining attention for their potential to combat resistant pathogens. This study aimed to evaluate the antibacterial activity of Morus alba (white mulberry) extracts and investigate their action mechanisms using proteomic analysis.

Methods

Leaf and stem samples of M. alba were extracted using both decoction and maceration techniques with water and ethanol as solvents. The antibacterial activity against MRSA was assessed through minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and time-kill assays. Chemical profiling of the most

SUBMITTER: Reamtong O 

PROVIDER: S-EPMC12834118 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature