Overlap between body composition abnormalities and sex-specific prognostication in decompensated cirrhosis.

ABSTRACT:

Purpose

We aimed to demonstrate distinct body composition (BC) profiles stratified by sex and clarify their joint effects on long-term mortality in a retrospective cohort of inpatients.

Methods

Various BC parameters annotated on computed tomography (CT) images at the third lumbar vertebra were used to define sarcopenia, myosteatosis, low subcutaneous adiposity, and high visceral adiposity. These categories were constructed using sex-specific, outcome-based cutoffs in a prerequisite manner.

Results

Among 519 patients hospitalized for acute decompensating episodes, the median age was 64.0 years, with a slight female predominance (51.6%). Among the female patients, high visceral adiposity was the most prevalent single BC abnormality (38.4%), while the most common overlap

SUBMITTER: Yang J 

PROVIDER: S-EPMC12834759 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature