FT3 Levels and Systemic Inflammation: Evidence From a Population-Based NHANES Analysis.

ABSTRACT:

Objective

Previous studies suggest a complex interaction between 3,3',5-triiodo-L-thyronine (T3) and inflammation, but this relationship remains unclear. This study investigates the association between free triiodothyronine (FT3) levels and inflammatory markers in the US population using National Health and Nutrition Examination Survey (NHANES) data.

Methods

This study analyzed NHANES data from three cycles between 2007 and 2012, using Spearman correlation tests and multivariate linear regression. Subgroup analyses and interaction tests were conducted based on age, gender, race, body mass index (BMI), thyroid-stimulating hormone, and free thyroxine (T4) to determine the correlations between FT3 and seven systemic inflammatory markers: C-reactive protein (CRP), neutrophil-to-

SUBMITTER: Yang L 

PROVIDER: S-EPMC12835195 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature