Altered static and dynamic amplitude of low-frequency fluctuations in acute carbon monoxide poisoning patients: a resting-state fMRI study.

ABSTRACT:

Objective

This study aimed to investigate alterations in brain activity due to acute carbon monoxide poisoning (ACOP) and their relationship with clinical manifestations using static and dynamic amplitude of low-frequency fluctuation (ALFF) analyses.

Methods

Resting-state functional magnetic resonance imaging (fMRI) and clinical data were obtained from 31 ACOP patients and 28 healthy controls. The static ALFF value and dynamic ALFF variability were measured and compared between groups. Partial correlation analysis explored the relationships between changes in ALFF and clinical features in ACOP patients.

Results

ACOP patients exhibited increased dynamic ALFF in the bilateral superior frontal gyrus (SFG) and left middle frontal gyrus (MFG) and decreased static ALFF in t

SUBMITTER: Wang S 

PROVIDER: S-EPMC12835238 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature