Social determinants of health and Helicobacter pylori infection prevalence: a systematic review and meta-analysis.

ABSTRACT:

Objective

Helicobacter pylori infection represents a major public health challenge. While its transmission risk is potentially influenced by social determinants of health (SDoH), existing evidence remains fragmented. This study aimed to systematically evaluate the associations between various SDoH and Helicobacter pylori infection risk under a unified mapping framework and to explore the major sources of heterogeneity.

Methods

We systematically searched PubMed, EMBASE, and Web of Science from inception to July 2025. Observational studies in human populations were included. SDoH were standardized into binary categories based on pre-defined rules. The prevalence of Helicobacter pylori and crude odds ratios (cORs) were pooled separately using random-effects

SUBMITTER: Wang H 

PROVIDER: S-EPMC12835281 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature