Influence of anesthetic agent and burst suppression on postoperative delirium in elderly patients: a prospective cohort study with automated EEG analysis.

ABSTRACT:

Background

Guidelines currently suggest considering EEG guidance during general anesthesia in elderly patients to avoid prolonged burst suppression (BS), with the aim of mitigating postoperative delirium (POD). Our study aimed to investigate the association between POD and intraoperative BS duration dependent on the general anesthetic agent used (propofol vs. sevoflurane).

Methods

In this prospective study (2019-2022), EEGs from 265 patients over 70 years undergoing general anesthesia were analyzed for intraoperative BS duration both visually and using one new automated algorithm to evaluate its accuracy. Associations between BS duration, anesthetic agent, and postoperative delirium (POD) were evaluated using multivariable logistic regression, adjusting for confounders.

R

SUBMITTER: Markus M 

PROVIDER: S-EPMC12835323 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature