Structural MRI Differences in the Thalamus, Caudate Nucleus, and Interthalamic Adhesion in Dogs With Idiopathic Epilepsy.

ABSTRACT: Structural changes in the thalamus and basal nuclei (BN) have been documented in magnetic resonance imaging (MRI) studies of human epilepsy. Studies that specifically investigate whether equivalent structural changes exist in dogs with idiopathic epilepsy (IE) are limited. This retrospective study evaluated the morphology of the caudate nucleus and thalamus in dogs with IE (n = 40) compared to a control group (n = 38) using standard MRI studies. Measurements of the interthalamic adhesion (ITA) thickness and area, thalamic area and volume, and caudate nucleus area and volume were made to compare the size and symmetry of these structures between groups. Dogs with IE had a significantly larger ITA thickness (p < 0.0001) and area (p < 0.0001), smaller thalamic area (p < 0.0001) and volume (p <

SUBMITTER: Chan TY 

PROVIDER: S-EPMC12835456 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature