Association of Psychiatric Disorder Comorbidities With Global and Orbital Ablative Surgeries: A Real-World Retrospective Cohort Study.

ABSTRACT:

Objective

To assess the incidence and risk of psychiatric disorders, including depression, anxiety, and trauma-related disorders, in individuals who underwent globe and orbital ablative surgeries compared to a matched control group.

Methods

This retrospective cohort study used Korean National Health Insurance Service data. The cohort included 338,767 individuals, with 16,545 in the surgery group (orbital exenteration, enucleation, or evisceration, 2003-2021) and 322,222 matched controls. After exclusions, 12,965 patients were matched with 251,445 controls via propensity score matching. The cumulative incidence and risk of psychiatric disorders, including depression (F32.x, F34.0, F34.1), anxiety (F40.x, F41.x), and trauma-related disorders (F43.x), over three years post-surg

SUBMITTER: Jung S 

PROVIDER: S-EPMC12835631 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature