Carboxydotrophic Acetogenesis in Alkaline Conditions Results in Transient Formate Production by the Halo-Alkaliphilic Acetogen Haloacetibacter carboxydivorans Gen. Nov. sp. Nov.

ABSTRACT: Carboxydotrophic acetogens are found widespread in the environment, yet the strains characterised to date are almost exclusively mild acidophiles or neutrophiles, often isolated from gut or freshwater systems. Here, we describe a novel carboxydotrophic halo-alkaliphilic, acetogenic bacterium, strain MD4, isolated from a CO-fed bioreactor operated under high salt and alkaline conditions. Phylogenetic analysis suggests that strain MD4 is the first representative of a novel genus, branching between the Alkalibacter and Alkalibaculum genera, for which we propose the name Haloacetibacter carboxydivorans. The bacterium tolerates a wide range of sodium (0.01-2.5 M) and pH (7-10), but was not exceptionally tolerant to metals such as copper, nickel and cobalt. During growth on CO, strain MD4 produc

SUBMITTER: Diender M 

PROVIDER: S-EPMC12835891 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature