Impact of low-grade inflammation on neurological outcomes in patients with acute pontine infarction: a retrospective cohort study.

ABSTRACT:

Background

Acute pontine infarction significantly impacts neurological function and prognosis. Recent studies suggest that low-grade inflammation (LGI) may play a critical role in influencing recovery outcomes. However, the relationship between LGI and neurological prognosis in acute pontine infarction remains underexplored.

Objectives

This study aims to investigate the correlation between LGI and neurological outcomes in patients with acute pontine infarction over 90 days post-stroke.

Methods

A retrospective cohort study was conducted involving 502 patients diagnosed with acute pontine infarction at The First People's Hospital of Foshan between January 1, 2015, and July 14, 2022. Clinical data, inflammatory markers (CRP, WBC, NLR, PLT), and neurological function asse

SUBMITTER: Zhu J 

PROVIDER: S-EPMC12835896 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature