Optical coherence tomography angiography reveals insights into complementary vascular and neurodegenerative mechanisms in multiple sclerosis.

ABSTRACT: Optical coherence tomography angiography quantifies retinal microvasculature biomarkers, offering insights into neurovascular mechanisms underlying brain damage in multiple sclerosis. This study evaluated these potential mechanisms of neurodegeneration by examining associations between optical coherence tomography and optical coherence tomography angiography metrics, brain volumes and clinical outcomes in people with multiple sclerosis. This cross-sectional study included multiple sclerosis patients from a prospective cohort. Participants underwent optical coherence tomography/optical coherence tomography angiography, vision and clinical assessments and brain MRI. Age- and sex-matched controls underwent optical coherence tomography/optical coherence tomography angiography. The OCTA Vascula

SUBMITTER: Yam CH 

PROVIDER: S-EPMC12835921 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature