Comparing standard and technology-assisted peer-delivered CBT for perinatal depression: A causal mediation study.

ABSTRACT: The ENHANCE non-inferiority trial that took place in a deprived setting in Pakistan demonstrated that a technology-assisted digital adaptation of the Technology Assisted Thinking Healthy Programme (THP-TAP) was no different than the face-to-face THP in improving symptoms of perinatal depression. The present study examines the mechanisms through which THP-TAP improved symptoms of perinatal depression (or not) compared to the face-to-face THP. We applied a counterfactual-based approach to mediation - particularly interventional effects - to decompose the total effect of the THP-TAP intervention on symptoms of perinatal depression into the following pre-specified indirect effects: number of sessions attended; behavioural activation; perceived social support; problem-solving and cognitive-rest

SUBMITTER: Waqas A 

PROVIDER: S-EPMC12835944 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature