Umbilical Cord Blood pH Level, Apgar Score, and Attention-Deficit/Hyperactivity Disorder.

ABSTRACT:

Importance

Perinatal hypoxia is an important cause of neurodevelopmental impairment and may thus be associated with attention-deficit/hyperactivity disorder (ADHD). In population-based studies, hypoxia is often assessed by Apgar score alone; however, criteria for relevant perinatal hypoxia require both clinical and biochemical abnormalities (eg, a low Apgar score and a low umbilical cord blood pH level).

Objectives

To identify full-term and near-term newborns exposed to hypoxia by combining the Apgar score and the umbilical cord blood pH level and to investigate their association with ADHD.

Design, setting, and participants

This cohort study, with follow-up from birth until December 31, 2022, identified all singleton newborns with a gestational age of 35 weeks or more

SUBMITTER: Pedersen MV 

PROVIDER: S-EPMC12836134 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature