Core variables for real-world clinicogenomic data collection in precision oncology.

ABSTRACT:

Background

Precision oncology evidence gaps may be bridged using real-world clinicogenomic data; however, current limitations compromise real-world data collection and evidence generation. We aimed to define a set of precision oncology core variables that can aid in fit-for-purpose real-world data collection to be used for a range of purposes and by various stakeholders based on the approach adopted when designing the WAYFIND-R registry (NCT04529122).

Materials and methods

A panel of precision oncology experts created a list of variables based on standard dictionaries and vocabularies, which was aligned with the European Medical Agency's draft guidelines for registry-based studies. A list of core variables was selected from the initial broad list of variables.

Results

SUBMITTER: Dienstmann R 

PROVIDER: S-EPMC12836595 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature