Transferability of Real World Evidence to Support HTA Recommendations in Lower Income European Countries.

ABSTRACT:

Background and aims

Lower income European countries (LIECs) have more limited financial resources to cover high-cost technologies in rare diseases than higher income European countries (HIECs). Our study explores how treatment recommendations in myelodysplastic syndrome (MDS) can be supported in LIECS by transferring real-world evidence (RWE) generated by target trial emulation (TTE) method in HIECs.

Method

In the HTx project transferability aspects of the MDS case study were considered upfront. HTA agency consortium partners set expectations for the MDS case study team on how to integrate the new TTE methodology into the routine work of HTA bodies. In consecutive workshops consortium members and external HTA experts identified the main challenges of transferring evidence ge

SUBMITTER: Kalo Z 

PROVIDER: S-EPMC12836872 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature