Retinal Vasculature in Schizophrenia Spectrum Disorder.

ABSTRACT: The purpose of this research is to determine whether retinal vasculatures differ between participants with schizophrenia spectrum disorder (SSD) and controls. Ninety participants (51 SSD, mean age 35.8 ± 13.5, and 39 controls, mean age 35.5 ± 11.4) underwent 3 × 3 mm² macular and 6 × 6 mm² optic nerve head (ONH) optical coherence tomography angiography (OCTA) scans. En face macula and ONH region images were divided into quadrants, binarized, and then skeletonized. Skeletonized vessel densities were compared between our two groups. Additionally, the foveal avascular zone (FAZ) size and acircularity index were compared between the two groups. There was significantly decreased vessel density in the temporal region of the ONH in the SSD group compared to controls (p

SUBMITTER: Sherman CS 

PROVIDER: S-EPMC12837173 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature