Systolic blood pressure time in target range within 24 h and in-hospital death of critically ill patients and the role of ventricular arrhythmias: a MIMIC-IV analysis with external validation in the eICU-CRD database.

ABSTRACT:

Background

The stability of blood pressure control is crucial in critically ill patients. Systolic blood pressure (SBP) time in target range (TTR) has been recognized as an emerging dynamic assessment indicator of blood pressure, but its prognostic value in critically ill patients remains unclear.

Methods

This retrospective cohort study utilized data from the MIMIC-IV database, including adult patients with their first intensive care unit (ICU) admission. SBP TTR within 110-140 mmHg during the first 24 h was calculated. The primary outcome was in-hospital all-cause mortality, and the secondary outcome was ventricular arrhythmias (VA, including FPVCs, VT, and VF). Logistic regression, restricted cubic splines, subgroup analyses, receiver operating characteristic (ROC) curve a

SUBMITTER: Shen Q 

PROVIDER: S-EPMC12837325 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature