A new risk-stratified scoring system for predicting left atrial appendage thrombus in patients with nonvalvular atrial fibrillation.

ABSTRACT:

Background

The predictive capacity of the CHA2DS2-VASc score for left atrial appendage thrombus (LAAT) detection in nonvalvular atrial fibrillation (NVAF) patients shows significant limitations.

Objective

To recognize predictors of LAAT and create a more precise risk-assessment model.

Methods

Between January 2019 and December 2023, consecutive NVAF patients without a previous history of anticoagulation who underwent transesophageal echocardiography were recruited from two centers. Clinical data, biomarker information, and transthoracic echocardiographic parameters were collected in a standardized manner. The derivation cohort comprised patients from one center, while the validation cohort consisted of participants from the other center.

Results

1505 patients (m

SUBMITTER: Liu J 

PROVIDER: S-EPMC12837345 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature