Rectal Colonization by Carbapenemase-Producing Enterobacterales in a Tertiary Care Hospital in Havana, Cuba.

ABSTRACT: Introduction: Rectal colonization by carbapenemase-producing carbapenem-resistant Enterobacterales (CP-CRE) is a risk factor for subsequent infections, which are associated with high mortality rates. Methods: A cross-sectional study was conducted. Rectal swabs were collected from 297 patients within 48 h of admission to eight high-prevalence CP-CRE hospital departments, with follow-up swabs taken weekly for up to 4 weeks. Species identification, antimicrobial susceptibility testing, and genetic detection of carbapenemases were performed. The genetic relationship among isolates was assessed using ERIC-PCR, combined with epidemiological data, to investigate subsequent infections. Results: Fecal carriage of CP-CRE was detected in 15.5% (46/297) of patients- All car

SUBMITTER: Yu H 

PROVIDER: S-EPMC12837422 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature