Training in flexible, intensive insulin management to enable dietary freedom in people with type 1 diabetes: dose adjustment for normal eating (DAFNE) randomised controlled trial.

ABSTRACT:

Objectives

To evaluate whether a course teaching flexible intensive insulin treatment combining dietary freedom and insulin adjustment can improve both glycaemic control and quality of life in type 1 diabetes.

Design

Randomised design with participants either attending training immediately (immediate DAFNE) or acting as waiting list controls and attending "delayed DAFNE" training 6 months later.

Setting

Secondary care diabetes clinics in three English health districts.

Participants

169 adults with type 1 diabetes and moderate or poor glycaemic control.

Main outcome measures

Glycated haemoglobin (HbA(1c)), severe hypoglycaemia, impact of diabetes on quality of life (ADDQoL).

Results

At 6 months, HbA(1c) was significantly better in immediate DAFNE p

SUBMITTER: DAFNE Study Group 

PROVIDER: S-EPMC128375 | biostudies-literature | 2002 Oct

REPOSITORIES: biostudies-literature