The value of translational therapy in the treatment of advanced hepatoid adenocarcinoma of stomach.

ABSTRACT:

Background

Advanced hepatoid adenocarcinoma of stomach still lacks effective and standardized treatment options. This study aims to explore the therapeutic value of translational therapy in advanced hepatoid adenocarcinoma of stomach.

Methods

We conducted a retrospective analysis of 37 patients with advanced hepatoid adenocarcinoma of stomach who successfully underwent translational therapy followed by surgical intervention between October 2009 and October 2024. Through survival analysis and Cox regression, we identified the clinicopathological factors that significantly impact patient prognosis.

Results

The median survival time of 37 patients was 39.0 months. 70.3% of patients achieved R0 resection, with an average OS 93.8 months and a 5-year survival rate of 64.4%.

SUBMITTER: Chen L 

PROVIDER: S-EPMC12837953 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature