A meta analysis of pulmonary vein isolation compared with additional ablation strategies for atrial fibrillation.

ABSTRACT:

Background

Pulmonary Vein Isolation (PVI) is considered to be the primary strategy for atrial fibrillation (AF) ablation. However, recurrence of AF and atrial tachycardia was observed to occur often after PVI, which led to the proposition of performing additional ablations such as linear lesions, left atrial (LA) posterior wall isolation, substrate modification, and electrocardiogram (EGM)-based approaches as add-ons to PVI or alternative strategies. While numerous randomized controlled trials have been conducted in this regard, the efficacy of these strategies compared with PVI alone has been ambiguous, with some trials showing significant improvement and others showing no superiority over PVI alone. Thus, a systematic review and meta-analysis were conducted to address this ambigu

SUBMITTER: Saleem MM 

PROVIDER: S-EPMC12837986 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature