Long-Term Stable Biosensing Using Multiscale Biostructure-Preserving Metal Thin Films.

ABSTRACT: Microparticle detection technology uses materials that can specifically recognize complex biostructures, such as antibodies and aptamers, as trapping agents. The development of antibody production technology and simplification of sensing signal output methods have facilitated commercialization of disposable biosensors, making rapid diagnosis possible. Although this contributed to the early resolution of pandemics, traditional biosensors face issues with sensitivity, durability, and rapid response times. We aimed to fabricate microspaces using metallic materials to further enhance durability of mold fabrication technologies, such as molecular imprinting. Low-damage metal deposition was performed on target protozoa and Norovirus-like particles (NoV-LPs) to produce thin metallic films that ad

SUBMITTER: Takemura K 

PROVIDER: S-EPMC12838530 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature