Engineered PVA Hydrogel as a Universal Platform for Developing Stable and Sensitive Microbial BOD-Biosensors.

ABSTRACT: Polyvinyl alcohol (PVA) hydrogels modified through radical polymerization under UV irradiation and Ce⁴⁺ ion treatment were investigated as a potential platform for developing highly sensitive biosensors for rapid biochemical oxygen demand analysis in water. These modifications enhance PVA physicochemical properties, including mechanical strength, stability, and biocompatibility, making it promising for immobilizing microorganisms in bioanalytical systems. A dual-mediator biosensor system using ferrocene (FC) and neutral red (NR) was developed with yeast Blastobotrys adeninivorans immobilized in modified PVA. The FC+NR-B. adeninivorans-PVA-Ce⁴⁺ system exhibited high sensitivity (linear range of 0.1-3.81 mgO₂/dm³), selectivity, and op

SUBMITTER: Medvedeva A 

PROVIDER: S-EPMC12839383 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature