Orthostatic Tremor Is Evoked by Muscle Load Without the Need for Orthostatic Position.

ABSTRACT:

Background

Primary orthostatic tremor (POT) is a rare movement disorder characterized by a high-frequency tremor and a considerable feeling of unsteadiness. People with POT are significantly affected in their daily activities and have reduced quality of life. The tremor occurs in standing position and dominates in the lower extremities. However, whether an orthostatic position is essential for evoking the tremor has not been fully clarified.

Objectives

To investigate how POT is responding to muscle load in non-orthostatic positions.

Methods

In this work, we measured the tremor in POT patients using a smartphone running a tremor analysis application attached to the proximal fibula in supine, seated and standing position, as well as when they were subjected to muscle lo

SUBMITTER: Af Edholm K 

PROVIDER: S-EPMC12839475 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature