The Mild Behavioral Impairment Checklist for Parkinson's Disease: An Ancillary Instrument in Cognitive Assessment.

ABSTRACT:

Background

Mild behavioral impairment (MBI) is a syndrome characterized by the later-life onset of neuropsychiatric symptoms (NPS) and serves as a potential marker for dementia. In Parkinson's disease (PD), MBI has been associated with worse cognition, cortical atrophy, and altered connectivity. Unlike existing instruments that assess NPS in PD, the MBI Checklist (MBI-C) leverages sustained behavioral changes to identify patients at risk of cognitive impairment and neurodegeneration. The 34-item MBI-C has yet to be validated in PD.

Objective

This study assesses the MBI-C's psychometric properties in a multicenter Canadian PD sample and proposes a revised version optimized for PD.

Methods

A total of 406 PD patients from the Canadian Open Parkinson Network were assessed

SUBMITTER: Pinilla-Monsalve GD 

PROVIDER: S-EPMC12839493 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature