Uncovering the Molecular Response of Oregano (Origanum vulgare L.) to ¹²C⁶⁺ Heavy-Ion Irradiation Through Transcriptomic and Metabolomic Analyses.

ABSTRACT: Origanum vulgare L., a medicinal herb rich in bioactive phenols and terpenes, is recognized for its anti-inflammatory and antimicrobial properties. Heavy-ion beam mutagenesis, a sophisticated breeding technique, can induce significant variations in plants, thereby affecting their secondary metabolite production. This study utilized metabolomic and transcriptomic approaches to investigate the effects of ¹²C⁶⁺ heavy-ion irradiation on oregano. Our results indicated substantial changes in mutant lines, including marked alterations in plant height, leaf morphology, and biomass accumulation. Metabolomic analysis indicated that the differentially accumulated volatile compounds were primarily terpenoids. Furthermore, transcriptomic analysis indicated a predominant enr

SUBMITTER: Tan Z 

PROVIDER: S-EPMC12839708 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature