Survival Prediction in Septic ICU Patients: Integrating Lactate and Vasopressor Use with Established Severity Scores.

ABSTRACT:

Background

Accurate prediction of survival in septic patients remains a major challenge in intensive care medicine. Established severity scores such as the Acute Physiology and Chronic Health Evaluation II (APACHE II) and the Sequential Organ Failure Assessment (SOFA) are widely used to estimate prognosis, while biochemical markers such as serum lactate may provide complementary information. However, the prognostic interplay between these scores, lactate dynamics, vasopressor requirement, and infection focus has not been fully elucidated in septic populations.

Methods

We conducted a retrospective observational study of 146 adult patients with sepsis admitted to the intensive care unit (ICU) of the Hospital Clínico Universitario de Valladolid (HCUV), Spain, between 2022 and 2

SUBMITTER: Andres CMC 

PROVIDER: S-EPMC12839871 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature