Differences in Management of Neonates with Hypoxic-Ischemic Encephalopathy (HIE) by Level of Neonatal Care Provided at Birth: Insights from a Referral-Based Cohort in the Canton of Zurich, Switzerland.

ABSTRACT: Background/Objectives: Neonates with hypoxic-ischemic encephalopathy (HIE) are born in delivery facilities with different levels of neonatal care. The objective of this study was to investigate differences in the incidence of HIE and postnatal management between different levels of neonatal care in delivery facilities. Methods: This is a retrospective, multi-center cohort study of neonates with moderate-to-severe HIE receiving therapeutic hypothermia (TH) in the Canton of Zurich, Switzerland, registered in the Swiss National Asphyxia and Cooling Register between 2015 and 2023. Incidences of HIE receiving TH were calculated for all delivery facilities according to the national levels of neonatal care on site (Level I-basic; Level IIB-intermediate (no Level IIA facility in the

SUBMITTER: Erni L 

PROVIDER: S-EPMC12839900 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature